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Deus Ex (2000)

Author: Eidos Montréal

This game is not just one of the greatest sci-fi games of all time, but one of the best games, period. You're thrown into the cyberpunk world under protagonist JC Denton. Augmented with nano-chips, you must recover the vaccine of a dangerous man-made virus and stop the terrorist organization responsible for its theft. That responsibility leads to a blend of stealth, action, and hacking, making your way through skillfully designed levels in whatever way you please. It has the masterful touch of Warren Spector, known for greats like System Shock, Thief, and more. Great gameplay is nothing without a complimentary story, however, and Deus Ex easily delivers that. It's one of the most multi-layered, twisting stories in gaming, complete with some of the best voice actors and a compelling soundtrack. It would be a terrible shame for any sci-fi fan to miss out on this title.